• The Secret Life of Walter Mitty (2006) (announced)**** Walter Mitty
• Untitled Harold Ramis/Owen Wilson Project (2006) (announced)
• Date School (2006) (announced)
• Outsourced (2006) (announced)
• You, Me and Dupree (2006) (pre-production)
• Cars (2006) (filming) (voice)**** Lightning McQueen
• Danny Roane: First Time Director (2005) (filming)**** Owen
• Wedding Crashers (2005)**** John Beckwith
• The Wendell Baker Story (2005)**** Neil King
• The Mirror (2005)
• Meet the Fockers (2004)**** Kevin Rawley
• The Life Aquatic with Steve Zissou (2004)**** Ned Plimpton
• Around the World in 80 Days (2004)**** Wilbur Wright
• Starsky & Hutch (2004)**** Ken Hutchinson
• The Big Bounce (2004)**** Jack Ryan
• Shanghai Knights (2003)**** Roy O'Bannon
• I Spy (2002)**** Alex Scott
... aka I-Spy (USA: promotional title)
• Behind Enemy Lines (2001)**** Lt. Chris Burnett
• The Royal Tenenbaums (2001)**** Eli Cash
• Zoolander (2001)**** Hansel McDonald/Leonard Mortimer Weitzman
... aka Zoolander (Germany)
• Meet the Parents (2000)**** Kevin Rawley
• Shanghai Noon (2000)**** Roy O'Bannon
• The Haunting (1999)**** Luke Sanderson
... aka Maldicion, La (USA: Spanish title)
• Breakfast of Champions (1999)**** Monte Rapid
• The Minus Man (1999)**** Vann Siegert
• Heat Vision and Jack (1999) (TV) (voice)**** Voice Of Heat Vision/Doug
• Rushmore (1998) (uncredited)**** Edward Applebee
• Permanent Midnight (1998)**** Nicky
• Armageddon (1998)**** Oscar Choi, Geologist
• Anaconda (1997)**** Gary Dixon
... aka Anaconda (Peru)
• The Cable Guy (1996)**** Robin's date
• Bottle Rocket (1996) (as Owen C. Wilson)**** Dignan
• Bottle Rocket (1994)**** Dignan